What is Tramadol? Tramadol is used to treat moderate to severe pain. The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.

Tramadol dosage. This is a typical dosing schedule for someone just starting to take tramadol regular-release tablets:

  • Your doctor will most likely start with 25 milligrams (mg) each morning.
  • That may increase by separate doses of 25 mg every three days to reach a maximum dose of 100 mg a day (25 mg, four times a day), depending on how much the medication is relieving your pain.
  • If necessary, your doctor may increase by separate doses of 50 mg every three days to reach a maximum of 200 mg a day (50 mg, four times a day).
  • A normal adult dose should not go above 400 mg a day.
  • For someone with cirrhosis (liver damage), the daily dose should not be above 100 mg in a 24-hour period.
  • For someone with kidney disease, the daily dose should not be above 200 mg.
  • For someone older than 75, the daily dose should not be above 200 mg.