What is Revlimid (Lenalidomide)? Revlimid (lenalidomide) affects the immune system. It promotes immune responses to help slow tumor growth. Revlimid is used to treat multiple myeloma (bone marrow cancer), either in combination with another medicine or after stem cell transplant. Revlimid is also used to treat anemia (a lack of red blood cells) in patients with myelodysplastic syndrome caused by an abnormal chromosome. This disorder is also called deletion 5q MDS because part of chromosome 5 is missing. In people with this disorder, the bone marrow does not produce enough healthy blood cells.