What is Keppra (Levetiracetam)? Keppra (Levetiracetam) is an anti-epileptic drug, also called an anticonvulsant. Keppra is used as adjunctive therapy to treat partial onset seizures in adults and children 1 month of age and older with epilepsy. Keppra is also used to treat tonic-clonic seizures in adults and children who are at least 6 years old, and myoclonic seizures in adults and children who are at least 12 years old.