Depakote (Divalproex sodium) dosage:

  • The recommended starting dose of Depakote for the treatment of mania in bipolar disorder is 750 mg daily.
  • The recommended starting of Depakote for the treatment of complex partial seizures is 10 to 15 mg/kg/day.
  • The recommended starting dose of Depakote for the treatment of absence seizures is 15 mg/kg/day.
  • The recommended starting dose of Depakote for the prevention of migraine is 250 mg twice daily.