Missed dose of Cipro (Ciprofloxacin). Take ciprofloxacin exactly as directed by your doctor. Don’t stop taking ciprofloxacin on your own. Skipping doses or stopping too soon can result in a more severe infection that is harder to treat. If you miss a dose of ciprofloxacin, take the missed dose as soon as you remember. If it’s almost time for your next regular dose, however, skip the missed dose. Don’t double your dose to make up for the missed one.