How to take Breo Ellipta. Use Breo Ellipta inhalation powder exactly as prescribed by your doctor. Follow all directions on your prescription label. Breo Ellipta is a powder that comes with a special inhaler device preloaded with blister packs containing measured doses of the medicine. The device opens and loads a blister of fluticasone and vilanterol each time you use the inhaler. The disk device is not to be used with a spacer. Follow the patient instructions provided with the inhaler device.