What is Atorvastatin (Lipitor)? Atorvastatin is in a group of drugs called HMG CoA reductase inhibitors, or “statins.” Atorvastatin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors. Atorvastatin is used in adults and children who are at least 10 years old.